Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia

PHASE2RecruitingINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

February 1, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

July 1, 2029

Conditions
Sever Aplastic AnaemiaElderly (People Aged 65 or More)Immunosuppressive Treatment
Interventions
DRUG

Dose-attenuated IST and Hetrombopag

Porcine-ATG : 15 mg/kg/day IV ×5 days. Cyclosporine : 3-5 mg/kg/day (adjusted to trough 100-200 μg/L). Hetrombopag: 15 mg daily for 24weeks.

Trial Locations (1)

Unknown

RECRUITING

Red Blood Cell Diseases Center, Tianjin

All Listed Sponsors
lead

Institute of Hematology & Blood Diseases Hospital, China

OTHER