NCT07007221View on ClinicalTrials.gov

Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

December 1, 2030

Study Completion Date

December 1, 2030

Conditions
DepressionHiv
Interventions
DRUG

Metformin

12 weeks of Metformin 1000mg

DRUG

Metformin

12 weeks of Metformin 1500mg

DRUG

Metformin

8 weeks of Metformin

OTHER

Placebo

8 weeks placebo drug

DRUG

Metformin

12 weeks of Metformin

DRUG

Fluoxetine

12 weeks of Fluoxetine

DRUG

Metformin+Fluoxetine

12 weeks of Metformin+Fluoxetine

OTHER

double placebo

12 weeks of double placebo

All Listed Sponsors
lead

University of Minnesota

OTHER