NCT07006194View on ClinicalTrials.gov

Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP)

NANot yet recruitingINTERVENTIONAL

Enrollment

360

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions

Glaucoma

Interventions

DIETARY_SUPPLEMENT

Nicotinamide Tablet

One nicotinamide tablet per day during the month preceding surgery

Trial Locations (3)

56124

U.O. Oculistica Universitaria, Pisa

66100

Clinica Oftalmologica - Ospedale Clinicizzato SS Annunziata di Chieti, Chieti Scalo

07100

Clinica Oculistica AOU Sassari, Sassari

All Listed Sponsors

collaborator

OFFHEALTH S.p.A.

INDUSTRY

collaborator

Università degli Studi di Sassari

OTHER

collaborator

University of Pisa

OTHER

lead

Università degli Studi 'G. d'Annunzio' Chieti e Pescara

OTHER

NCT07006194 - Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP) | Biotech Hunter | Biotech Hunter