Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality

NARecruitingINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Hip Fractures
Interventions
DRUG

Esketamine combined with dexmedetomidine

After successful neuraxial anesthesia, 0.125mg/kg esketamine and 0.3ug/kg dexmedetomidine are diluted into 30ml of normal saline and continuously pumped for 20 minutes, then connected to a micropump: 15ug/kg/h esketamine 0.02ug/kg/h dexmedetomidine to 96ml saline, continuous amount: 2ml/h, continuous pumping for 48h.

DRUG

Normal saline

After successful neuraxial anesthesia, 30ml of normal saline was continuously pumped for 20 minutes, followed by a micropump: 96ml of saline, continuous amount: 2ml/h for 48h.

Trial Locations (1)

Unknown

RECRUITING

Peking University Shenzhen Hospital, Shenzhen

All Listed Sponsors
lead

Peking University Shenzhen Hospital

OTHER

NCT07002723 - Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality | Biotech Hunter | Biotech Hunter