226
Participants
Start Date
June 1, 2025
Primary Completion Date
June 1, 2027
Study Completion Date
June 1, 2029
QL1706 (bispecific antibody targeting PD-1 and CLTA-4)
QL1706: 5 mg/kg intravenously every 3 weeks until disease progression or intolerable toxicity, with a maximum duration of 2 years.
Bevacizumab
Bevacizumab : 15 mg/kg intravenously every 3 weeks until disease progression or intolerable toxicity, with a maximum duration of 22 cycles.
carboplatin
Carboplatin: AUC=5, intravenously every 3 weeks until disease progression or intolerable toxicity, with a maximum duration of 6 cycles
Paclitaxel
Paclitaxel: 175 mg/m\^2 intravenously every 3 weeks until disease progression or intolerable toxicity, with a maximum duration of 6 cycles
Tongji Hospital, Wuhan
Chinese Academy of Medical Sciences
OTHER
Peking Union Medical College Hospital
OTHER
Fudan University
OTHER
Sun Yat-sen University Cancer Center (SUSUCC)
UNKNOWN
Peking University Cancer Hospital & Institute
OTHER
Peking University People's Hospital
OTHER
First Affiliated Hospital, Sun Yat-Sen University
OTHER
The Second Affiliated Hospital, Sun Yat-sen University
UNKNOWN
Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Renmin Hospital of Wuhan University
OTHER
Zhejiang Provincial People's Hospital
OTHER
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
OTHER
Shanghai First Maternity and Infant Hospital
OTHER
Hubei Cancer Hospital
OTHER
Sir Run Run Shaw Hospital
OTHER
Wuhan Central Hospital
OTHER
Zhejiang Cancer Hospital
OTHER
The First Affiliated Hospital of Zhengzhou University
OTHER
Third Affiliated Hospital of Zhengzhou University
OTHER
Henan Provincial People's Hospital
OTHER
Henan Cancer Hospital
OTHER_GOV
Jiangsu Cancer Institute & Hospital
OTHER
The International Peace Maternity & Child Health Hospital of China welfare institute
UNKNOWN
Women's Hospital School Of Medicine Zhejiang University
OTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
First Affiliated Hospital of Zhejiang University
OTHER
Tongji Hospital
OTHER