Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

October 1, 2026

Study Completion Date

December 1, 2026

Conditions
PsychosisCannabis Use
Interventions
DRUG

Metformin

Metformin will be prescribed, reaching 1000mg/day (a standard dose). This will be done under the principal investigator's care and the patient's clinical team, including assessment of metformin adherence. Metformin will be prescribed for 6 months. Antipsychotic treatment will continue as per standard of care (metformin as adjunct therapy), as well as routine follow up.

All Listed Sponsors
collaborator

Dalhousie University

OTHER

lead

Nova Scotia Health Authority

OTHER