Role of Silymarin in Neuroprotection and Symptom Management in Parkinson's Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

May 10, 2025

Primary Completion Date

May 30, 2026

Study Completion Date

May 30, 2026

Conditions
Parkinson Disease
Interventions
DRUG

levodopa-carbidopa

Carbidopa/levodopa is a combination of two medications: carbidopa and levodopa. It is primarily used to manage the symptoms of Parkinson's disease. The main and most effective treatment strategy for motor symptoms in Parkinson's disease relies on replenishing dopamine levels through the use of L-dopa.

DRUG

Silymarin

Silymarin, a polyphenolic flavonoid renowned for its potent antioxidant properties, is employed clinically for managing hepatic disorders. Its antioxidant effects are primarily attributed to its ability to scavenge free radicals.

Trial Locations (1)

31511

RECRUITING

Tanta Hospital for Mental Health, Tanta

All Listed Sponsors
collaborator

Prof. Sahar Kamal Hegazy,Head of Clinical Pharmacy Department,Faculty of Pharmacy,Tanta University

UNKNOWN

collaborator

Dr. Raed Ahmed Abdel-Maboud,Lecturer of neurology,Faculty of Medicine,Tanta University

UNKNOWN

lead

Tanta University

OTHER