EFFECTS OF A YERBA MATE EXTRACT IN REDUCING METABOLIC SYNDROME IN OVERWEIGHT INDIVIDUALS

NANot yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

June 10, 2025

Primary Completion Date

December 1, 2026

Study Completion Date

December 1, 2029

Conditions
Metabolic SyndromeDiabetesOxidative StressDyslipidemiaInflamation
Interventions
DIETARY_SUPPLEMENT

Intervention with yerba mate extract or placebo

The standardized extract of yerba mate (Ilex paraguariensis) will be supplied by Sustentec. It is a dry extract of the plant's green, powdered leaves, obtained through aqueous extraction. The extract was obtained by infusing the dried leaves of the plant and the drying process was carried out using a spray-dryer (ratio 6/1 leaves/extract). The extract will be encapsulated containing 250 mg each. Administration Intervention group: 2,250 mg of standardized yerba mate extract will be administered in 9 capsules, 3 times a day, just before the main meals. This amount will provide approximately 980 mg of caffeoylquinic acids/day, which was defined based on the estimated usual intake of caffeoylquinic acids by individuals in a municipality in the southern region of the country, from traditional drinks made with yerba mate (chimarrão and tereré) (Gebara et al., 2017). Placebo group: 9 capsules containing maltodextrin will be administered 3 times a day, just before the main meals.

Trial Locations (1)

85770-000

Universidade Federal da Fronteira Sul, Realeza

All Listed Sponsors
collaborator

Itaipu Technological Park (ITP)

NETWORK

collaborator

Fundação Araucária

OTHER

lead

Universidade Federal da Fronteira Sul

OTHER

NCT07000825 - EFFECTS OF A YERBA MATE EXTRACT IN REDUCING METABOLIC SYNDROME IN OVERWEIGHT INDIVIDUALS | Biotech Hunter | Biotech Hunter