The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke)

NANot yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

December 31, 2026

Conditions
Stroke Patients With Hemiplegia or Hemiparesis in the Subacute Stage
Interventions
DEVICE

The AscenZ-VIII Stimulator (Investigational Medical Device)

Sham tPCS current will be delivered through Channel 1, while active TENS treatment delivered through Channel 2, 3 and 4 of The AscenZ-VIII Stimulator via surface electrodes. The placement of electrodes will be exactly the same as the active tPCS montage.

DEVICE

The AscenZ-VIII Stimulator (Investigational Medical Device)

This group will receive active TENS treatment delivered through Channel 2, 3 and 4 of The AscenZ-VIII Stimulator via 6\*9cm Silica gel electrodes on top of the tPCS that is delivered through Channel 1. The placement of the electrodes will be on the part of the spinal segment innervating the lower limbs (L1-L5), the adductor muscles and the gastrocnemius muscles.

Trial Locations (2)

119228

National University Hospital, Singapore

159964

Alexandra Hospital, Singapore

All Listed Sponsors
lead

National University Health System, Singapore

OTHER

NCT06999876 - The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke) | Biotech Hunter | Biotech Hunter