Minimally Invasive Protocols for the Treatment and Control of Caries Lesions in Children and Adolescents

NANot yet recruitingINTERVENTIONAL
Enrollment

2,500

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Dental Caries
Interventions
PROCEDURE

Fluoride Varnish Application (Preventive Protocol)

Single application of Duraphat® fluoride varnish on permanent molars and incisors, repeated every 3 months.

PROCEDURE

Fluoride Varnish for Active Enamel Lesions

Weekly fluoride varnish applications for 4 weeks, followed by quarterly maintenance applications.

PROCEDURE

Atraumatic Restorative Treatment (ART) Sealant

Sealant placement with high-viscosity glass ionomer using the ART technique, with quarterly fluoride varnish.

PROCEDURE

Atraumatic Restorative Treatment (ART)

Manual caries removal and cavity restoration with glass ionomer cement, followed by fluoride varnish every 3 months.

All Listed Sponsors
lead

University of Nove de Julho

OTHER

NCT06999005 - Minimally Invasive Protocols for the Treatment and Control of Caries Lesions in Children and Adolescents | Biotech Hunter | Biotech Hunter