Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support

NARecruitingINTERVENTIONAL
Enrollment

372

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

November 30, 2026

Conditions
Prescribing Patterns, PhysicianPhysician's Practice PatternsDrug Utilization Review
Interventions
BEHAVIORAL

Algorithmic Defaulting (Indication-Based Default)

PPIs are frequently overprescribed, and the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority.

BEHAVIORAL

Active Physician Choice

PPIs are frequently overprescribed, and the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether requiring providers to actively select prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority.

Trial Locations (1)

90024

RECRUITING

UCLA Health System, Los Angeles

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of California, Los Angeles

OTHER

NCT06998966 - Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support | Biotech Hunter | Biotech Hunter