60
Participants
Start Date
June 1, 2025
Primary Completion Date
August 10, 2025
Study Completion Date
August 10, 2025
taVNS
"Patients will receive taVNS at left tragus (a device developed by the Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education (School of Life Science and Technology, Xidian University), in collaboration with the Wearable BCI and Intelligent Rehabilitation Innovation Lab (Guangzhou Institute of Technology, Xidian University)) twice daily (morning and night) for 30 minutes per session over a period of up to 7 days. The stimulation parameters are as follows:~* Duty circle: 30s on periods alternating with 30s off periods;~* Frequency: 25 Hz;~* Amplitude: 0-2 mA (adjusted to the maximum tolerated level for each patient);~* Pulse width: 0.5 ms."
Sham-taVNS
"Patients will receive taVNS at left earlobe (a device developed by the Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education (School of Life Science and Technology, Xidian University), in collaboration with the Wearable BCI and Intelligent Rehabilitation Innovation Lab (Guangzhou Institute of Technology, Xidian University)) twice daily (morning and night) for 30 minutes per session over a period of up to 7 days. The stimulation parameters are as follows: \*Duty circle: 30s on periods alternating with 30s off periods; \*Frequency: 25 Hz; \*Amplitude: 0-2 mA (adjusted to the maximum tolerated level for each patient); \*Pulse width: 0.5 ms."
RECRUITING
Shaanxi Second People's Hospital, Xi'an
RECRUITING
Xijing Hospital of Digestive Diseases, Xi'an
RECRUITING
Department of Gastroenterology , Tangdu Hospital , Fourth Military Medical University, Xi'an
RECRUITING
Department of Gastroenterology, 986 Hospital of Xijing Hospital, Fourth Military Medical University, Xi'an
RECRUITING
The 980th Hospital of the PLA Joint Logistics Support Force (Primary Bethune International Peace Hospital of PLA), Shijiazhuang
Air Force Military Medical University, China
OTHER