Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Acute Pancreatitis

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

August 10, 2025

Study Completion Date

August 10, 2025

Conditions
Acute Pancreatitis (AP)Vagus Nerve Stimulations
Interventions
DEVICE

taVNS

"Patients will receive taVNS at left tragus (a device developed by the Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education (School of Life Science and Technology, Xidian University), in collaboration with the Wearable BCI and Intelligent Rehabilitation Innovation Lab (Guangzhou Institute of Technology, Xidian University)) twice daily (morning and night) for 30 minutes per session over a period of up to 7 days. The stimulation parameters are as follows:~* Duty circle: 30s on periods alternating with 30s off periods;~* Frequency: 25 Hz;~* Amplitude: 0-2 mA (adjusted to the maximum tolerated level for each patient);~* Pulse width: 0.5 ms."

DEVICE

Sham-taVNS

"Patients will receive taVNS at left earlobe (a device developed by the Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education (School of Life Science and Technology, Xidian University), in collaboration with the Wearable BCI and Intelligent Rehabilitation Innovation Lab (Guangzhou Institute of Technology, Xidian University)) twice daily (morning and night) for 30 minutes per session over a period of up to 7 days. The stimulation parameters are as follows: \*Duty circle: 30s on periods alternating with 30s off periods; \*Frequency: 25 Hz; \*Amplitude: 0-2 mA (adjusted to the maximum tolerated level for each patient); \*Pulse width: 0.5 ms."

Trial Locations (5)

710000

RECRUITING

Shaanxi Second People's Hospital, Xi'an

710032

RECRUITING

Xijing Hospital of Digestive Diseases, Xi'an

710038

RECRUITING

Department of Gastroenterology , Tangdu Hospital , Fourth Military Medical University, Xi'an

710054

RECRUITING

Department of Gastroenterology, 986 Hospital of Xijing Hospital, Fourth Military Medical University, Xi'an

050082

RECRUITING

The 980th Hospital of the PLA Joint Logistics Support Force (Primary Bethune International Peace Hospital of PLA), Shijiazhuang

All Listed Sponsors
lead

Air Force Military Medical University, China

OTHER

NCT06998784 - Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Acute Pancreatitis | Biotech Hunter | Biotech Hunter