276
Participants
Start Date
May 16, 2025
Primary Completion Date
May 8, 2028
Study Completion Date
May 8, 2028
Phacovitrectomy
Participants will undergo phacovitrectomy to remove the lens (phacoemulsification and intraocular lens implantation) and to repair the RRD (vitrectomy). Although a phacovitrectomy is done in the same manner whether the condition to be treated is macular hole or RRD, the calculations required for the surgeon to select which intraocular lens should be implanted are different if there is a RRD with a detached macula. For this reason, a Standard Operating Procedure (SOP) will be prepared for the phacovitrectomy group to guide surgeons on how to best determine the intraocular lens under these circumstances (17). Vitrectomy with any gauge size (e.g.23g, 25g, 27g) will be allowed for the surgery, as per standard care at the participating site. The choice of the tamponade agent will be at the discretion of the treating vitreoretinal surgeon, as per standard care.
Vitrectomy
Participants will receive vitrectomy to repair their RRD. The vitrectomy would be done as per standard care. Vitrectomy with any gauge size (e.g.23g, 25g, 27g) will be allowed for the surgery, as per standard care at the participating site. The choice of the tamponade agent will be at the discretion of the treating vitreoretinal surgeon, as per standard care. Then, if a cataract develops, phacoemulsification and intraocular lens implantation will be done as per standard clinical practice.
RECRUITING
Buckinghamshire Healthcare NHS Trust, Aylesbury
NOT_YET_RECRUITING
Belfast Health and Social Care Trust, Belfast
NOT_YET_RECRUITING
Sandwell and West Birmingham Hospitals NHS Trust, Birmingham
NOT_YET_RECRUITING
Bradford Teaching Hospitals NHS Foundation Trust, Bradford
NOT_YET_RECRUITING
University Hospitals Bristol NHS Foundation Trust, Bristol
NOT_YET_RECRUITING
County Durham and Darlington NHS Foundation Trust, Darlington
NOT_YET_RECRUITING
NHS Greater Glasgow & Clyde, Glasgow
NOT_YET_RECRUITING
Hull University Teaching Hospitals NHS Trust, Hull
NOT_YET_RECRUITING
The Leeds Teaching Hospitals NHS Trust, Leeds
NOT_YET_RECRUITING
University Hospitals Leicester NHS Trust, Leicester
NOT_YET_RECRUITING
Liverpool University Hospitals NHS Foundation Trust, Liverpool
NOT_YET_RECRUITING
Barts Health NHS Trust, London
NOT_YET_RECRUITING
Guys & St Thomas NHS Foundation Trust, London
NOT_YET_RECRUITING
King's College Hospital NHS Foundation Trust, London
NOT_YET_RECRUITING
Moorfields Eye Hospital NHS Foundation Trust, London
NOT_YET_RECRUITING
Manchester University NHS Foundation Trust, Manchester
NOT_YET_RECRUITING
South Tees Hospitals NHS Foundation Trust, Middlesbrough
NOT_YET_RECRUITING
Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne
NOT_YET_RECRUITING
Oxford University Hospitals NHS Foundation Trust, Oxford
NOT_YET_RECRUITING
University Hospitals Plymouth NHS Trust, Plymouth
NOT_YET_RECRUITING
Royal Berkshire NHS Foundation Trust, Reading
NOT_YET_RECRUITING
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield
NOT_YET_RECRUITING
University Hospital Southampton NHS Foundation Trust, Southampton
NOT_YET_RECRUITING
South Tyneside and Sunderland NHS Trust, Sunderland
NOT_YET_RECRUITING
Mid & South Essex NHS Foundation Trust, Westcliff-on-Sea
NOT_YET_RECRUITING
The Royal Wolverhampton NHS Trust, Wolverhampton
NOT_YET_RECRUITING
York and Scarborough Teaching Hospitals NHS Foundation Trust, York
Collaborators (1)
Northern Ireland Clinical Trials Unit
OTHER
Queen's University, Belfast
OTHER