NCT06997731View on ClinicalTrials.gov

Clinical Efficacy of Local Delivery of Minocycline and Hyaluronan Gel to Treat Periodontitis in Diabetic Patients

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 20, 2023

Primary Completion Date

January 1, 2025

Study Completion Date

February 1, 2025

Conditions
Periodontitis and DiabetesPeriodontitis
Interventions
PROCEDURE

Non -surgical treatment and oral hygiene instruction

Scaling and root planing which involves mechanical removal of sup-gingival calculus and necrotic cementum. Tis will be associated with oral hygiene instruction in the form of twice daily brushing for 2 minutes.

DRUG

Application of minocycline and hyaluronic acid gel.

application of minocycline and Gengigel® topical gel twice weekly for 3-week 1cc for each.

DRUG

local application of placebo gel

The placebo gel will be applied in the periodontal pocket twice weekly for 3-week 1cc for each.

Trial Locations (1)

Unknown

Enas Elgendy, Tanta

All Listed Sponsors
lead

Kafrelsheikh University

OTHER

NCT06997731 - Clinical Efficacy of Local Delivery of Minocycline and Hyaluronan Gel to Treat Periodontitis in Diabetic Patients | Biotech Hunter | Biotech Hunter