A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients

NANot yet recruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

May 20, 2025

Primary Completion Date

May 31, 2027

Study Completion Date

December 31, 2027

Conditions
PostoperativePulmonaryComplications
Interventions
DEVICE

Transpulmonary pressure-guided individualized PEEP

Transpulmonary pressure-guided individualized PEEP group was an intraoperative ventilation strategy based on esophageal pressure (Pes) monitoring of transpulmonary pressure-guided ventilation, using a small tidal volume (6-8 ml/kg of ideal body weight), maintaining the transpulmonary pressure in the safe range of 5-15 cmH2O PEEP for Pes+1 cm H2O level.

All Listed Sponsors
lead

Tianjin Medical University Cancer Institute and Hospital

OTHER