NCT06994455View on ClinicalTrials.gov

Efficacy of Local Doxycycline Gel Delivery Versus Doxycycline Nanoparticles Prepared Gel in The Treatment of Stage II Periodontitis

NAActive, not recruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

June 2, 2024

Primary Completion Date

August 31, 2025

Study Completion Date

September 30, 2025

Conditions
Periodontitis
Interventions
PROCEDURE

scaling and root planing along with antibiotic intervention

doxycycline gel exhibits bacteriostatic activity against prevalent periodontal pathogens

PROCEDURE

scaling and root planing along with antibiotic intervention

the formulation of doxycycline and incorprating it with PLGA nano-particles will increase the absorption rate in gingival sulcus

PROCEDURE

scaling and root planing

control group in the study

Trial Locations (1)

0000

Mansoura, Egypt, 35516, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER

NCT06994455 - Efficacy of Local Doxycycline Gel Delivery Versus Doxycycline Nanoparticles Prepared Gel in The Treatment of Stage II Periodontitis | Biotech Hunter | Biotech Hunter