ENGAGE: Virtual Reality-based Psychotherapy for Negative Symptoms in Schizophrenia

NAActive, not recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 9, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

May 31, 2026

Conditions
Schizophrenia Spectrum DisordersNegative Symptoms in Schizophrenia
Interventions
BEHAVIORAL

Virtual Reality-based psychotherapy

"A manualized, modularized, Virtual Reality-based intervention comprising 10 sessions of 1 hour each. The VR therapy aims at enhancing anticipatory pleasure and positive emotions by amplifying exposure and reactivity towards social environments and rewarding activities using a highly elaborate VR software. The VR exposure comprises several different virtual social environments (e.g., a bus, a café, a park etc.) In a tailored treatment approach, therapists will guide participants to train focusing on positive stimuli, engage in activities, experience social rewards, and practice expressing emotions through body language.~The therapy focuses on increasing the awareness of positive outcomes that may influence motivation. The therapy deploys activity appraisal/re-appraisal intended to enhance the salience of future opportunities for reward and desire for such rewards, thus targeting reward anticipation processes and promoting enjoyable daily-life activities."

Trial Locations (1)

2900

Copenhagen Research Center for Mental Health (CORE), Mental Health Services CPH, Denmark, Hellerup

All Listed Sponsors
collaborator

CNSR, Glostrup Psychiatric Center

UNKNOWN

lead

Mental Health Services in the Capital Region, Denmark

OTHER

NCT06993831 - ENGAGE: Virtual Reality-based Psychotherapy for Negative Symptoms in Schizophrenia | Biotech Hunter | Biotech Hunter