Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control Trial

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

November 11, 2024

Primary Completion Date

October 1, 2026

Study Completion Date

October 1, 2026

Conditions
SufentanilMorphineValiditySafetyOliceridine
Interventions
DRUG

Oliceridine

a loading dose of 1.5 mg of oliceridine was intravenously injected. Ten minutes later, an intravenous analgesic pump of 0.01 mg.kg-1.h-1 oliceridine was connected with normal saline to 100 ml at a rate of 2 ml per hour

DRUG

Morphine

a loading dose of 4 mg of morphine was intravenously injected. Ten minutes later, an intravenous analgesic pump of 0.03 mg.kg-1.h-1 morphine was connected with normal saline to 100 ml at a rate of 2 ml per hour

DRUG

Sufentanil

A 4 ug loading dose of sufentanil was intravenously injected. Ten minutes later, an intravenous analgesic pump of 0.03 ug.kg-1 h-1 was connected. sufentanil was mixed with normal saline to 100 ml at a rate of 2 ml per hour

Trial Locations (1)

246003

RECRUITING

Department of Anqing Hospital Anesthesiology, Anqing

All Listed Sponsors
lead

Anqing Municipal Hospital

OTHER