Comparative Effectiveness of Different Techniques for Repeat Ablation of Atrial Fibrillation

NANot yet recruitingINTERVENTIONAL
Enrollment

630

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

January 1, 2030

Study Completion Date

December 31, 2031

Conditions
Atrial Fibrillation (AF)
Interventions
PROCEDURE

Pulmonary Vein Isolation (PVI) without Left Atrial Posterior Wall Isolation (PWI)

"A doctor inserts a thin, flexible tube (called a catheter) through a blood vessel, usually in the groin, and guides it to the heart.~Once the catheter is in place, the doctor uses pulsed field electroporation, heat (radiofrequency) or cold (cryoablation) to create small scars in the area where the pulmonary veins connect to the left atrium of the heart.~These scars block the faulty electrical signals that cause AF, helping the heart maintain a normal rhythm."

PROCEDURE

Pulmonary Vein Isolation (PVI) with Left Atrial Posterior Wall Isolation (PWI)

PVI with an additional step where the doctor also isolates the back wall (posterior wall) of the left atrium.

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

University of Rochester

OTHER

NCT06988202 - Comparative Effectiveness of Different Techniques for Repeat Ablation of Atrial Fibrillation | Biotech Hunter | Biotech Hunter