Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

June 19, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
FrailtySarcopeniaSarcopenia in ElderlyMuscle StrengthPost Operative ComplicationsNutrition AssessmentRisk AssessmentElderly (People Aged 65 or More)Hand Strength
Interventions
DIAGNOSTIC_TEST

Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing

"Participants will undergo a structured frailty and muscle-strength assessment battery performed during their routine preoperative evaluation. These assessments serve as the primary exposure measures of interest and include:~Clinical Frailty Scale (CFS) evaluation (functional frailty assessment) Respiratory muscle strength assessment (Maximal Inspiratory Pressure (MIP) and Maximal Expiratory Pressure (MEP) using a MicroRPM handheld respiratory pressure meter) Hand-grip strength measurement (using Jamar dynamometer) Physical performance evaluation (Timed Up-and-Go (TUG) test) Skeletal muscle mass estimation (Bioelectrical impedance analysis, InBody 120) Muscle thickness measurement (Rectus femoris muscle thickness using portable ultrasound) Cognitive function screening (Mini-Cog test) Nutritional risk screening (Perioperative Nutrition Screen \[PONS\]) No additional interventions beyond these observational assessments will be conducted."

Trial Locations (1)

27599

RECRUITING

University of North Carolina, Chapel Hill

All Listed Sponsors
lead

University of North Carolina, Chapel Hill

OTHER