62
Participants
Start Date
May 18, 2025
Primary Completion Date
June 1, 2029
Study Completion Date
June 1, 2029
Toripalimab
Toripalimab 240 mg, administered on the first day, Q3W × 17 cycles
Capecitabine
Capecitabine 650 mg/m2 twice a day, oral administration, d1-21, Q3W × 17 cycles
salvage surgery
"The specific steps of high-frequency electrosurgical knife treatment for localized recurrent nasopharyngeal carcinoma are as follows:~1. It must be performed under general anesthesia, with the complete resection of the nasopharyngeal tumor and its sufficient safe boundary through both nasal cavities under the guidance of nasal endoscopy. When marking the surgical margin, the anterior margin should reach 1-2cm in front of the posterior column of the nasal septum, and the upper margin can reach about 0.5-1cm to the upper margin of the posterior nostril. The lateral and lower margins are designed individually based on the size and location of the tumor. The basic principle is to ensure a safe margin of 0.5-1.0cm, and then use low-temperature plasma ablation. Ablate the tumor tissue and the normal tissue at the resection margin layer by layer from the upper resection margin to the lower resection margin until no obvious tumor residue was observed with the naked eye.~2. Rinse the surgical c"
Sun Yat-sen University
OTHER