Vascular Function and Oxidative Stress in Emergency Medical Responders

NARecruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

May 14, 2025

Primary Completion Date

September 30, 2025

Study Completion Date

October 31, 2025

Conditions
Cardiovascular Function in EMTs
Interventions
DIETARY_SUPPLEMENT

Antioxidant cocktail

"Participants will take two doses of antioxidant supplements in capsule form during their overnight shift: the first dose at 7:00 PM, and the second dose 1.5 hour before their morning vascular function visit (post-shift). Each dose will consist of the following concentrations of antioxidants:~600 mg of α-lipoic acid, 1,000 mg of vitamin C, and 600 IU of vitamin E."

DIETARY_SUPPLEMENT

Placebo

Participants will take two doses of antioxidant supplements in capsule form during their overnight shift: the first dose at 7:00 PM, and the second dose 1.5 hour before their morning vascular function visit (post-shift). Each dose will consist of placebo pills made from microcrystalline cellulose, designed to match the antioxidants in taste, color, and appearance.

Trial Locations (1)

19713

RECRUITING

University of Delaware, Newark

All Listed Sponsors
lead

University of Delaware

OTHER