NCT06983678View on ClinicalTrials.gov

Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

NANot yet recruitingINTERVENTIONAL
Enrollment

132

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

March 31, 2030

Study Completion Date

March 31, 2030

Conditions
Tobacco UseChronic Pain
Interventions
BEHAVIORAL

Smoking as usual fMRI session

Participants in this condition will continue smoking as usual prior to the fMRI session

BEHAVIORAL

Abstinent fMRI session

Participants in this condition will be asked to abstain from smoking or using any other tobacco products for 24 hours prior to the fMRI session

Sponsors

Lead Sponsor

Duke University
All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Duke University

OTHER