100
Participants
Start Date
November 18, 2024
Primary Completion Date
February 28, 2027
Study Completion Date
February 28, 2027
Cerebral imaging (MRI) according to a dedicated protocol with central MRI reading
Cerebral MRI according to dedicated protocol, central MRI reading.
Determination of circulating biomarkers
High-throughput molecular analysis will be performed on plasma samples collected assessing a selected panel of biomarkers, associated with endothelial cell profiles using automated and high-throughput ELISA. The interactions between mutation profile, protein biomarkers, and clinical variables will be correlated with patients' outcomes.
RECRUITING
Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy, Milan
ACTIVE_NOT_RECRUITING
Istituto di Ricerche Farmacologiche Mario Negri, Milan
NOT_YET_RECRUITING
Policlinico di Bari, Bari
RECRUITING
Careggi Hospital, Firenze, Florence
NOT_YET_RECRUITING
Istituto Giannina Gaslini, Genova, Genova
RECRUITING
"San Giovanni di Dio e Ruggi d'Aragona, Salerno", Salerno
Mario Negri Institute for Pharmacological Research
OTHER
Istituto Giannina Gaslini
OTHER
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
Azienda Ospedaliero-Universitaria Careggi
OTHER
University of Bari
OTHER
Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
OTHER
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
OTHER