DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

PHASE4RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

July 25, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions

Type 2 Diabetes

Interventions

DRUG

ertugliflozine

SGLT2i versus placebo

BEHAVIORAL

low salt diet

comparing low salt versus high salt diet

DRUG

placebo

placebo tablet

BEHAVIORAL

high salt diet

Trial Locations (2)

RECRUITING

Childrens hospital colorado, Denver

RECRUITING

Amsterdam UMC, Amsterdam

All Listed Sponsors

collaborator

Children's Hospital Colorado

OTHER

lead

Amsterdam UMC, location VUmc

OTHER