50
Participants
Start Date
May 12, 2025
Primary Completion Date
May 31, 2027
Study Completion Date
May 31, 2028
Time Zero Donor Heart Biopsy for Molecular Analysis
"This intervention involves obtaining a right ventricular myocardial biopsy from the donor heart at the time of organ procurement (Time Zero), prior to transplantation. The biopsy is divided into two parts: one for routine histopathological evaluation and the other preserved in RNAlater® for molecular analysis using microarray technology. This molecular profiling is designed to detect early tissue injury and gene expression patterns associated with graft viability and transplant outcomes. The intervention is performed only once per donor and does not alter the standard clinical care of the recipient."
RECRUITING
Medical University Vienna, Vienna
Alberta Transplant Applied Genomics Centre
UNKNOWN
Medical University of Vienna
OTHER