NCT06982183View on ClinicalTrials.gov

The Effects of Propranolol, Hydrocortisone, and Morphine on Military-Relevant Performance Outcomes

PHASE4RecruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

May 27, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Fear of SpidersAcute Stress Reaction
Interventions
DRUG

Propranolol

An administration of a 40-mg propranolol capsule immediately after tarantula exposure

DRUG

Hydrocortisone

An intramuscular administration of 62.5 mg/1 ml of hydrocortisone immediately after tarantula exposure

DRUG

Morphine

An intramuscular administration of 5 mg/1 ml of morphine immediately after tarantula exposure

DRUG

Placebo (oral)

An administration of a placebo capsule after tarantula exposure

DRUG

Placebo (IM)

An intramuscular administration of 1 ml of saline immediately after tarantula exposure

Trial Locations (1)

20910

RECRUITING

Sleep Research Center (SRC), Walter Reed Army Institute of Research, Silver Spring

All Listed Sponsors
lead

Walter Reed Army Institute of Research (WRAIR)

FED