Study on the Treatment of Nonthrombotic Obstructive Pulmonary Hypertension

NARecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

February 10, 2025

Primary Completion Date

October 31, 2027

Study Completion Date

October 31, 2027

Conditions
Fibrosing MediastinitisPulmonary Hypertension
Interventions
PROCEDURE

Rituximab Lymph Node Injection Combined with Pulmonary Vascular Intervention

Based on the degree of vascular stenosis, individualized and periodic pulmonary vascular interventions are performed to reopen obstructed vessels. During the treatment cycle, one lymph node drug injection is administered: 50mg of rituximab is dissolved in 15ml of 5% glucose solution and injected at multiple sites into the identified enlarged mediastinal lymph nodes under ultrasound-guided bronchoscopy.

PROCEDURE

Pulmonary Vascular Interventional Therapy

According to the degree of vascular stenosis, individualized and periodic pulmonary vascular interventions are performed to reopen obstructed pulmonary vessels.

Trial Locations (1)

Unknown

RECRUITING

Beijing Chaoyang Hospital, Capital Medical University, Beijing

All Listed Sponsors
collaborator

Beijing Municipal Health Commission

OTHER_GOV

lead

Beijing Chao Yang Hospital

OTHER