The 'Bone-Brain' Crosstalk Mechanism of Subchondral Bone Nociceptive Sensitization Activating SPP1-Positive Microglia in the vlPAG Region Elucidates the Theoretical Connotation of Treating Knee Osteoarthritis Based on Kidney Differentiation

Not yet recruitingOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

June 15, 2025

Primary Completion Date

December 30, 2026

Study Completion Date

December 30, 2026

Conditions
Osteoarthitis
All Listed Sponsors
lead

Jinchao Xu

OTHER

NCT06977282 - The 'Bone-Brain' Crosstalk Mechanism of Subchondral Bone Nociceptive Sensitization Activating SPP1-Positive Microglia in the vlPAG Region Elucidates the Theoretical Connotation of Treating Knee Osteoarthritis Based on Kidney Differentiation | Biotech Hunter | Biotech Hunter