PRIORITY-CONNECT 2 Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

564

Participants

Timeline

Start Date

August 25, 2025

Primary Completion Date

July 30, 2028

Study Completion Date

July 30, 2028

Conditions
Colorectal CancerColorectal Neoplasms
Interventions
BEHAVIORAL

Preoperative Exercise

Aerobic, Endurance, Respiratory, Muscle Strength, Education

BEHAVIORAL

Postoperative Exercise

Aerobic, Endurance, Respiratory, Muscle Strength, Education

DIETARY_SUPPLEMENT

Preoperative Nutrition

Malnutrition screening, Weight monitoring, Symptom management, Dietetic counselling, Nutrition support

DIETARY_SUPPLEMENT

Postoperative Nutrition

Malnutrition screening, Weight monitoring, Symptom management, Dietetic counselling, Nutrition support

BEHAVIORAL

Preoperative Psychology

CBT skills, Skills training, Emotional validation, Behavioural activation, Psycho-education

BEHAVIORAL

Postoperative Psychology

CBT skills, Skills training, Emotional validation, Behavioural activation, Psycho-education

OTHER

Preoperative Nursing

Risk management, Managing pain, Wound care, Bowel function, Surgical education

OTHER

Postoperative Nursing

Risk management, Managing pain, Wound care, Bowel function/Stoma management, Education

BEHAVIORAL

Preoperative Peer Support Group

"Fortnightly sessions moderated by a social worker including patients and carers:~Safe space, Share experiences/ideas, Support, Education"

BEHAVIORAL

Postoperative Peer Support Group

"Fortnightly sessions moderated by a social worker including patients and carers:~Safe space, Share experiences/ideas, Support, Education"

OTHER

Usual Care

All participants will receive usual care according to their health care team, which may consist of advice on smoking cessation, reduction of alcohol intake, nutritional counselling, and medical optimisation in the preoperative anaesthetic clinic visits.

Trial Locations (32)

2050

Chris O'Brien Lifehouse, Sydney

Royal Prince Alfred Hospital, Sydney

2139

Concord Repatriation General Hospital, Sydney

2145

Westmead Hospital, Sydney

2148

Blacktown Hospital, Sydney

2298

Calvary Mater Hospital, Newcastle

2305

John Hunter Hospital, Newcastle

2450

Coffs Harbour Health Campus, Coffs Harbour

2500

Wollongong Hospital, Wollongong

2650

Wagga Wagga Base Hospital, Wagga Wagga

3000

Peter MacCallum Cancer Centre, Melbourne

3004

Alfred Hospital, Melbourne

3011

Footscray Hospital, Melbourne

3030

Werribee Mercy Hospital, Melbourne

3050

Royal Melbourne Hospital, Melbourne

3065

St Vincent's Melbourne Hospital, Melbourne

3076

Northern Hospital Epping, Melbourne

3084

Austin Hospital, Melbourne

3128

Eastern (Box Hill) Hospital, Melbourne

3144

Cabrini Hospital, Melbourne

3220

University Hospital Geelong (Barwon Health), Geelong

3350

Grampians Health Ballarat Hospital, Ballarat

3550

Bendigo Health, Bendigo

4029

Royal Brisbane & Women's Hospital, Brisbane

4102

Princess Alexandra Hospital, Brisbane

4108

The Queen Elizabeth II Jubilee Hospital, Brisbane

4870

Cairns Hospital, Cairns

5000

Royal Adelaide Hospital, Adelaide

5042

Flinders Medical Centre, Adelaide

5092

Modbury Hospital, Adelaide

5112

Lyell McEwin Hospital, Adelaide

6000

Royal Perth Hospital, Perth

Sponsors
All Listed Sponsors
collaborator

The University of Sydney, Sydney, Australia

UNKNOWN

collaborator

Medical Research Future Fund

OTHER

lead

Surgical Outcomes Research Centre (SOuRCe)

NETWORK

NCT06976710 - PRIORITY-CONNECT 2 Trial | Biotech Hunter | Biotech Hunter