A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

PHASE3RecruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

July 9, 2025

Primary Completion Date

June 5, 2026

Study Completion Date

July 3, 2026

Conditions
Plaque Psoriasis
Interventions
DRUG

Zasocitinib

Zasocitinib tablets.

DRUG

Deucravacitinib

Deucravacitinib capsules.

DRUG

Placebo to match zasocitinib

Zasocitinib matching placebo tablets.

DRUG

Placebo to match deucravacitinib

Deucravacitinib matching placebo capsules.

Trial Locations (113)

1003

NOT_YET_RECRUITING

Health Center 4, Center of Diagnostics, Riga

1013

NOT_YET_RECRUITING

Health Center 4, Clinic of Dermatology, Riga

1113

NOT_YET_RECRUITING

Medical Centre Femiclinic EOOD, Sofia

1431

NOT_YET_RECRUITING

Diagnostic and Consulting Center Aleksandrovska EOOD, Sofia

1510

NOT_YET_RECRUITING

Medical Center Hera EOOD-Sofia, Sofia

1592

NOT_YET_RECRUITING

Diagnostic Consultative Center XXVIII - Sofia - EOOD, Sofia

1606

NOT_YET_RECRUITING

Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia, Sofia

2600

NOT_YET_RECRUITING

Medical Center Asklepii OOD, Dupnitsa

5300

NOT_YET_RECRUITING

Multiprofile Hospital For Active Treatment Dr Tota Venkova, Gabrovo

5400

NOT_YET_RECRUITING

Medical Center Unimed EOOD-Sevlievo, Sevlievo

5500

NOT_YET_RECRUITING

Medical Center Medconsult Pleven - Lovech Branch, Lovech

6300

NOT_YET_RECRUITING

Diagnostic Consultative Center Sveti Georgi EOOD, Haskovo

10128

RECRUITING

Markowitz Medical PLLC dba OptiSkin Medical, New York

13500

NOT_YET_RECRUITING

Office of Mireille Ruer-Mulard, MD, Martigues

20850

RECRUITING

Lawrence J Green, MD LLC, Rockville

27516

RECRUITING

University of North Carolina at Chapel Hill, Chapel Hill

33012

RECRUITING

Direct Helpers Research Center, Hialeah

33014

RECRUITING

San Marcus Research Clinic Inc, Miami Lakes

37072

RECRUITING

Goodlettsville Dermatology Research, Goodlettsville

42270

NOT_YET_RECRUITING

Centre Hospitalier Universitaire de Saint Etienne, Saint-Etienne

43209

RECRUITING

Bexley Dermatology Research - Probity - PPDS, Bexley

44718

RECRUITING

Apex Clinical Research Center, LLC - Canton, Canton

46250

RECRUITING

Dawes Fretzin Clinical Research Group, LLC, Indianapolis

48202

NOT_YET_RECRUITING

Henry Ford Health System, Detroit

53002

NOT_YET_RECRUITING

Pratia Pardubice, Pardubice

60077

RECRUITING

Endeavor Health Clinical Trials, Skokie

72037

NOT_YET_RECRUITING

Centre Hospitalier Le Mans, Le Mans

75235

RECRUITING

Reveal Research Institute, Dallas

76031

NOT_YET_RECRUITING

Hopital Charles Nicolle-1 Rue de Germont, Rouen

77401

RECRUITING

The University of Texas Health Science Center at Houston (UTHSC-H), Bellaire

89145

RECRUITING

JDR Dermatology Research, LLC, Las Vegas

90212

RECRUITING

Zenith Research, Inc., Beverly Hills

91403

RECRUITING

UNISON Clinical Trials (Shahram Jacobs md inc.), Sherman Oaks

92708

RECRUITING

First OC Dermatology Research Inc., Fountain Valley

72916-6103

RECRUITING

Johnson Dermatology, Fort Smith

71913-6475

RECRUITING

Burke Pharmaceutical Research, Hot Springs

06416

RECRUITING

Central Connecticut Dermatology, PLLC, Cromwell

06511

NOT_YET_RECRUITING

Yale University School of Medicine, New Haven

33607-6429

RECRUITING

Advanced Clinical Research Institute, Tampa

60008-3811

RECRUITING

Arlington Dermatology, Rolling Meadows

03756

RECRUITING

Dartmouth Hitchcock Medical Center, Lebanon

44124-4005

RECRUITING

Apex Clinical Research Center, LLC - Mayfield Heights, Mayfield Heights

15213-3403

NOT_YET_RECRUITING

UPMC Department of Dermatology, Pittsburgh

76011-3800

RECRUITING

Arlington Research Center, Arlington

77401-3505

RECRUITING

Bellaire Dermatology Associates, Bellaire

78213-2250

RECRUITING

San Antonio, San Antonio

78218-3128

RECRUITING

Texas Dermatology and Laser Specialists-San Antonio, San Antonio

77479-1001

RECRUITING

Houston Center for Clinical Research, LLC, Sugar Land

T3E 0B2

NOT_YET_RECRUITING

Beacon Dermatology - Probity, Calgary

T6H 4J8

NOT_YET_RECRUITING

VIDA Dermatology - Probity, Edmonton

V3V 0C6

RECRUITING

Enverus Medical Research - Probity, Surrey

V3V 6A7

RECRUITING

Dr Chih-Ho Hong Medical Inc, Surrey

R3M 3Z4

RECRUITING

Wiseman Dermatology Research Inc., Winnipeg

E3B 1G9

NOT_YET_RECRUITING

Brunswick Dermatology Centre - Probity, Fredericton

L8L 3C3

RECRUITING

Lima's Excellence In Allergy And Dermatology Research (Leader) Inc. - Probity, Hamilton

L8N 1Y2

RECRUITING

Dermatrials Research, Hamilton

L3P 1X3

RECRUITING

Lynderm Research Inc - Probity, Markham

P1B 3Z7

RECRUITING

North Bay Dermatology Center - Probity, North Bay

L6J 7W5

RECRUITING

The Centre for Clinical Trials Inc., Oakville

K9J 5K2

RECRUITING

Skin Centre for Dermatology, Peterborough

L4B 1A5

RECRUITING

The Centre For Dermatology, Richmond Hill

N2J 1C4

RECRUITING

Alliance Clinical Trials, Waterloo

N8T1E6

RECRUITING

XLR8 Medical Research, Windsor

H3Z 2S6

RECRUITING

Siena Medical Research Corporation, Montreal

S7K 2C1

RECRUITING

Skinsense Medical Research, Saskatoon

G1V 4X7

RECRUITING

Centre de Recherche Dermatologique du Quebec Metropolitain, Québec

741 01

NOT_YET_RECRUITING

Nemocnice AGEL Novy Jicin a.s, Nový Jičín

702 00

NOT_YET_RECRUITING

CCR Ostrava s.r.o., Ostrava

779 00

NOT_YET_RECRUITING

Dermskin s.r.o, Olomouc

602 00

NOT_YET_RECRUITING

Pratia Brno s.r.o. - PRATIA - PPDS, Brno

100 00

NOT_YET_RECRUITING

CLINTRIAL s.r.o., Prague

110 00

NOT_YET_RECRUITING

Prof. MUDr. Petr Arenberger, DrSc. - CRC - PPDS, Prague

150 00

NOT_YET_RECRUITING

Praglandia s.r.o., Prague

467-8602

RECRUITING

Nagoya City University Hospital, Nagoya

814-0180

RECRUITING

Fukuoka University Hospital, Fukuoka

811-3217

RECRUITING

Hino Dermatology Clinic, Fukutsu-shi

060-0033

RECRUITING

JR Sapporo Hospital, Sapporo

060-0063

RECRUITING

Investigational Product department, Sapporo

550-0006

RECRUITING

Nippon Life Hospital, Osaka

593-8324

RECRUITING

Investigational Product department Dermatology and Ophthalmology Kume Clinic, Sakai-shi

525-8585

RECRUITING

Seikoukai Omi Medical Center, Kusatsu-shi

329-0498

RECRUITING

Jichi Medical University Hospital, Shimotsuke-shi

104-8560

RECRUITING

St. Luke's International Hospital, Chuo-ku

160-0023

RECRUITING

Tokyo Medical University Hospital, Shinjuku-Ku

190-0023

RECRUITING

Medical Corporation Jitai-kai Tachikawa Dermatology Clinic, Tachikawa-shi

169-0073

RECRUITING

JCHO Tokyo Yamate Medical Center, Shinjuku-ku

933-0871

RECRUITING

Shirasaki Dermatology Clinic, Takaoka-shi

861-4101

RECRUITING

Ohyama Dermatology Clinic, Kumamoto

LV-3301

NOT_YET_RECRUITING

Semigallia, Kuldīga

LV-1001

NOT_YET_RECRUITING

Riga 1st Hospital, Riga

LV-1003

NOT_YET_RECRUITING

Aesthetic dermatology clinic of prof. J. Kisis, Riga

LV-1009

NOT_YET_RECRUITING

Veseliba un estetika Ltd., Riga

LV-1011

NOT_YET_RECRUITING

Outpatient Clinic Adoria, Riga

86-031

NOT_YET_RECRUITING

DermoDent Centrum Medyczne Aldona Czajkowska Rafal Czajkowski, s.c., Osielsko

31-501

NOT_YET_RECRUITING

Krakowskie Centrum Medyczne Sp. z o.o., Krakow

27-400

NOT_YET_RECRUITING

Dermedic Jacek Zdybski, Ostrowiec Swietokrzyski

50-566

RECRUITING

Cityclinic Przychodnia lekarsko psychologiczna Matusiak sp.p, Wroclaw

51-503

NOT_YET_RECRUITING

Centrum Columbus, Wroclaw

20-573

NOT_YET_RECRUITING

Luxderm Specjalistyczny Gabinet Dermatologiczny Dorota Krasowska, Lublin

00-874

NOT_YET_RECRUITING

MICS Centrum Medyczne Warszawa, Warsaw

Masovian Voivodeship

NOT_YET_RECRUITING

"Klinika Reuma Park Sp. z o.o. sp. k. , Centrum Medyczne Reuma Park"

02-677

RECRUITING

ETG Warszawa - PPDS, Warsaw

02-953

NOT_YET_RECRUITING

Klinika Ambroziak Dermatologia, Warsaw

35-055

NOT_YET_RECRUITING

Uniwersytecki Szpital Kliniczny im. Fryderyka Chopina w Rzeszowie, Rzeszów

15-879

NOT_YET_RECRUITING

ClinicMed Daniluk, Nowak Spolka Komandytowa, Bialystok

80-546

NOT_YET_RECRUITING

Centrum Badan Klinicznych Pi-house Sp. Z O. O., Gdansk

Warmian-Masurian Voivodeship

RECRUITING

"Ambulatorium Sp. z o.o. , Elblag, Poland"

229 40-600

NOT_YET_RECRUITING

NZOZ Holsamed-Oddział Libero, Katowice

10-117

NOT_YET_RECRUITING

ETYKA Osrodek Badan Klinicznych, Olsztyn

71-500

NOT_YET_RECRUITING

Twoja Przychodnia - Szczecinskie Centrum Medyczne, Szczecin

02 962

NOT_YET_RECRUITING

Royalderm Agnieszka Nawrocka, Warsaw

90-338

NOT_YET_RECRUITING

Centrum Terapii Współczesnej J.M. Jasnorzewska S.K.A., Lodz

90-436

NOT_YET_RECRUITING

Dermoklinika-Centrum Medyczne s.c, Lodz

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Takeda

INDUSTRY