The Effect of rs7903146 Genotype on Islet GLP-1 Production in Humans

PHASE2Not yet recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

March 1, 2029

Conditions

Genetic PredispositionType2diabetes

Interventions

BIOLOGICAL

Exendin 9-39

A competitive antagonist of the GLP-1 receptor

OTHER

Saline

Saline infusion will serve as an inactive comparator

Trial Locations (1)

Mayo Clinic in Rochester, Rochester