Quality of Recovery in Laparoscopic Sleeve Gastrectomy Using Dexmedetomidine Infusion Versus Laparoscopic TAP Block in Combination With Paragastric Neural Block

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 3, 2025

Primary Completion Date

June 4, 2025

Study Completion Date

June 20, 2025

Conditions
Laparoscopic Sleeve Gastrectomy
Interventions
DRUG

Dexmedetomidine infusion

Dexmedetomidine will be maintained at 0.5 μg/kg/h ideal body weight via a syringe pump until trocar removal.

PROCEDURE

Paragastric neural block

Paragastric neural block (PGNB) will be administered using a 25-gauge needle attached to a venous catheter extension, introduced through the left 12 mm port. Infiltration of 20 mL undiluted 0.5% bupivacaine will be performed at six levels in the fatty tissue of the paragastric area, including the lesser omentum, vagus nerve, esophago-gastric junction, proximal stomach, mid-stomach, distal antrum, hepatic artery, and left gastric artery, with the needle cap removed under direct vision throughout the procedure.

PROCEDURE

Laparoscopic Transversus Abdominis Plane (LTAP) block

LTAP will be administered after insufflation before insertion of the right and left-handed ports. 30 mL of 0.25% bupivacaine will be injected into the posterolateral subcostal regions on both sides. The correct placement will be confirmed by observing the spread of fluid between the transversus abdominis and the internal oblique muscle layers laparoscopically

Trial Locations (1)

Unknown

RECRUITING

Alexandria Main University Hospital, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER