The Effects of FMT on Intestinal Microbiota and Pulmonary Microecology

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

May 20, 2025

Primary Completion Date

November 15, 2026

Study Completion Date

December 31, 2026

Conditions
Lung InfectionMicrobial ColonizationFood Intolerance Syndromes
Interventions
OTHER

Fecal suspension (provided by SShanghai Chengge Pharmaceutical Technology Co., Ltd.)

Prepare 300 ml of intestinal flora suspension from 100-150 g of feces. Administer vancomycin 500 mg via nasogastric tube every 12 hours for 48-72 hours before FMT. Clean the intestines with 2000 ml of polyethylene glycol 24 hours before FMT (except for patients with diarrhea). Subjects can eat and drink freely during preparation but must fast for at least 2 hours before FMT (water allowed). No food or water is permitted within 2 hours after FMT. Stop all antibiotics (intravenous, oral, nebulized) at least 24 hours before FMT.

Trial Locations (1)

Unknown

RECRUITING

Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
lead

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER