To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure).

NANot yet recruitingINTERVENTIONAL
Enrollment

315

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 31, 2028

Study Completion Date

October 31, 2028

Conditions
Respiratory Failure With HypercapniaTherapeutic Bronchofiberoscopy
Interventions
DEVICE

Use of NIV during therapeutic FOB as a respiratory support method in patients with type 2 respiratory failure

The aim of the project is to assess the safety, indications and contraindications for therapeutic bronchofiberoscopy in patients with decompensated respiratory acidosis using: invasive mechanical ventilation (IMV), non-invasive mechanical ventilation (NIV) and high-flow nasal canulla (HFNC). Additionally, we want to determine to what extent the use of respiratory support during bronchofiberoscopy (BF) will avoid complications such as exacerbation of hypoxemia and/or acidosis and the occurrence of hemodynamic instability.

DEVICE

Use of HFNC during therapeutic FOB as a respiratory support method in patients with type 2 respiratory failure

The aim of the project is to assess the safety, indications and contraindications for therapeutic bronchofiberoscopy in patients with decompensated respiratory acidosis using: invasive mechanical ventilation (IMV), non-invasive mechanical ventilation (NIV) and high-flow nasal canulla (HFNC). Additionally, we want to determine to what extent the use of respiratory support during bronchofiberoscopy (BF) will avoid complications such as exacerbation of hypoxemia and/or acidosis and the occurrence of hemodynamic instability.

All Listed Sponsors
lead

Medical University of Silesia

OTHER

NCT06970041 - To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure). | Biotech Hunter | Biotech Hunter