Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Atrial FibrillationAtrial TachycardiaAtrial FlutterCongenital Heart DiseasePulmonary Vein IsolationPulsed Field AblationCatheter Ablation
Interventions
DEVICE

Pulsed field ablation using a pentaspline ablation catheter

After conclusion of AT ablation, transseptal or transbaffle puncture will be performed under fluoroscopic and intracardiac echocardiography guidance to access the left atrium (LA) or pulmonary venous atrium (PVA) if not already done so. PFA will be performed using a pentaspline catheter (Farawave, Boston Scientific) and a steerable sheath to achieve PVI of all veins draining to the LA/PVA with entrance and exit block confirmed at each vein. In patients where PFA is unable to achieve PVI, touch-up RFA will be performed. Programmed atrial stimulation will be performed to investigate for inducible atrial tachycardias. An implantable loop recorder will be placed at the conclusion of the procedure.

All Listed Sponsors
collaborator

Brigham and Women's Hospital

OTHER

lead

Boston Children's Hospital

OTHER

NCT06969378 - Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease | Biotech Hunter | Biotech Hunter