168
Participants
Start Date
June 1, 2025
Primary Completion Date
June 30, 2029
Study Completion Date
June 30, 2029
Massed Prolonged Exposure Therapy (M-PE)
Massed Prolonged Exposure (M-PE) is a trauma-focused, evidence-based behavioral intervention for posttraumatic stress disorder (PTSD). It is delivered over a compressed timeline (e.g., 10 sessions over 2-4 weeks) as opposed to weekly sessions over 3-4 months. This format has been shown to accelerate PTSD symptom reduction and reduce treatment dropout. In this study, M-PE will be delivered concurrently with an Intensive Outpatient Program (IOP) for substance use disorder (SUD) at Gateway Community Services. Sessions will be led by trained clinicians using a standardized PE protocol, with treatment including imaginal exposure, in vivo exposure, and processing.
Standard outpatient SUD care
"Patients randomized to usual care will receive standard intensive outpatient SUD treatment.~* Resilience group (weekly)~* Peer support~* Individual therapy from a variety of modalities"
Gateway Community Services, Jacksonville
National Institute of Mental Health (NIMH)
NIH
University of California, San Diego
OTHER
University of Minnesota
OTHER
Rutgers, The State University of New Jersey
OTHER