Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Open Rhinoplasty

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

May 12, 2025

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2025

Conditions
IntraoperativeKetamineMagnesium SulfatePostoperative AnalgesiaRhinoplasty
Interventions
DRUG

Ketamine and Magnesium Sulfate

Patients will receive a bolus of 0.5 mg/kg of ketamine given over a period of ten minutes followed by a constant infusion of 0.25 mg/kg/hr and a bolus dose of 30 mg/kg of magnesium sulfate during a 10-minute period followed by a continuous infusion of 9 mg/kg/hr.

DRUG

Saline 0.9%

Patients will receive saline 0.9% as a control group.

Trial Locations (1)

11591

RECRUITING

Ain Shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER