Lidocaine Infusion Versus Magnesium Infusion in Decreasing Fentanyl Requirements in Endoscopic Sinus Surgeries

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

May 10, 2025

Primary Completion Date

July 15, 2025

Study Completion Date

July 30, 2025

Conditions
Enhanced RecoveryFunctional Endoscopic Sinus SurgeryLidocaineMagnesium SulphatePerioperative Pain
Interventions
DRUG

Lidocaine group

25ml of lidocaine hydrochloride 2% will be added to 25 ml of standard saline 0.9% solution in a 50ml syringe to be infused via a syringe pump. The resultant concentration will be 10mg/ml. According to the calculated study drug dose, each patient will receive 0.2ml/kg/h

DRUG

Magnesium group

a 50ml syringe will be filled with magnesium sulfate solution (100mg/ml) to be infused via a syringe pump. According to the calculated study drug dose, each patient will receive 0.2ml/kg/h

DRUG

Control group

a 50ml syringe will be filled with a standard saline 0.9% solution to be infused via a syringe pump. Each patient will receive 0.2ml/kg/h

Trial Locations (1)

Unknown

Faculty of Medicine, Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER