40
Participants
Start Date
July 31, 2025
Primary Completion Date
July 31, 2027
Study Completion Date
July 31, 2028
Immediate G-POEM
Gastric POEM (G-POEM) performed under general anesthesia. A submucosal tunnel will be created along the greater curvature of the stomach to access the pyloric muscle under endoscopic vision. The pylorus will be incised at two locations with a dual myotomy between the 5 and 8 o'clock positions on the clock face
Delayed G-POEM
Participants will receive standard medical treatment, including prokinetic agents, antiemetics (ondansetron 8 mg twice daily), nutritional support, and dietary counseling. Laxative treatments will be prescribed as needed. After three months, participants will undergo G-POEM as described above
French Society of Digestive Endoscopy
OTHER