Use of Different Enteral Feeds to Impact on Chyle Leaks in Oesophagectomy

NANot yet recruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

May 5, 2025

Primary Completion Date

May 5, 2030

Study Completion Date

December 31, 2030

Conditions
Oesophageal Cancer
Interventions
DIETARY_SUPPLEMENT

MCT feeding

"MCT feeds will be initiated using Nutrison Peptisorb 1kcal/ml. Peptisorb has lower fat content, with a higher proportion of MCTs. The feeding protocol for both formulae will be the same, with equivalent rates of enteral feeding:~* Day 1: if no clinical contra-indication, commence feeding either with standard or MCT feeds at 20ml/hr for 24 hours. Feeds to commence at 8am.~* Day 2: if tolerating feeds continue feeds at 20ml/hr for 12 hours, then increase to 40ml/hr for 12 hours~* Day 3: if tolerating feeds increase feeds to 60ml/hr and await dietician review regarding target rate and duration.~By POD6, if there is no chyle leak, all patients will be given standard feeds for discharge home.~For oral feeding, if patients are progressing clinically, they will have restricted fluids on POD3, with introduction of diet in each group from day 4 onwards. This allows a direct comparison of chyle leak rates for 72h of regular vs MCT enteral feeding."

DIETARY_SUPPLEMENT

Standard feeds

Nutrison Protein Plus 1.25kcal/ml.

All Listed Sponsors
lead

Royal College of Surgeons, Ireland

OTHER