Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

PHASE4RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

June 4, 2025

Primary Completion Date

June 4, 2027

Study Completion Date

July 4, 2027

Conditions

Cleft PalatePainPostoperative CarePerioperative CareChildren

Interventions

DRUG

Methadone hydrochloride

Initial dosing 0.2mg/kg, potential to escalate to 0.25mg/kg following interim analysis

DRUG

Fentanyl/Hydromorphone

Per routine care

Trial Locations (1)

RECRUITING

Duke University Medical Center, Durham