322
Participants
Start Date
June 1, 2025
Primary Completion Date
December 12, 2027
Study Completion Date
June 1, 2028
C1-2 instrumentation
"Surgical fracture stabilization with a posterior screw-rod system from C1-2 from a posterior approach.~The routine surgery commonly lasts approximately 100 minutes and requires a hospital stay of about 6 days. An additional external bracing in the postoperative setting is not required."
External immobilization with rigid cervical collar
External immobilization with a rigid cervical collar for 12 weeks. Compliance is monitored through patient diaries, recognizing the real-world challenges of consistent brace use. Lack of adherence is considered to reflect routine clinical practice. A typical drawback of the conservative intervention in daily practice is the absolute reliance on patient compliance to wear the collar continuously for at least 12 weeks, which poses a significant challenge to this treatment strategy.
Charité University Hospital Berlin, Berlin
Center for Spinal Surgery and Neurotraumatology, Berufsgenossenschaftliche Unfallklinik, Frankfurt am Main
LMU University Hospital, Munich
Department of Neurosurgery, RWTH Aachen University, Aachen
Department of Neurosurgery and Spine Center, HELIOS Hospital Berlin Buch, Berlin
Department of Orthopaedic and Traumatology, University of Cologne, Cologne
Department of Orthopedics, Medical University at Dresden, Dresden
Department of Neurosurgery and Spine Surgery, University Hospital Essen, Essen
Department of Neurosurgery, University Medical Center Göttingen, Göttingen
Department of Trauma and Reconstructive Surgery, BG Klinikum Bergmannstrost Halle, Halle
Department of Neurosurgery, University Hospital Heidelberg, Heidelberg
Department of Neurosurgery, University Hospital of Lausitz, Lausitz
Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig, Leipzig
Spine Surgery, Orthopedic Hospital Markgröningen GmbH, Markgröningen
BG Trauma Centre, Eberhard Karls University of Tuebingen, Tübingen
Spine Center, St. Josefs-Hospital Wiesbaden, Wiesbaden
St. Josefs-Hospital Wiesbaden GmbH
OTHER
Medical University of Cologne
OTHER
BG Trauma Center Tuebingen
OTHER
RWTH Aachen University
OTHER
University Hospital Heidelberg
OTHER
University Hospital, Essen
OTHER
BG Klinikum Bergmannstrost, Halle, Germany
UNKNOWN
Helios Klinikum Berlin-Buch
OTHER
German Federal Ministry of Education and Research
OTHER_GOV
Charite University, Berlin, Germany
OTHER
Technical University of Munich
OTHER