Two Versus One Week Breast Radiotherapy (RT)

PHASE3RecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

April 29, 2025

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2040

Conditions
Breast Cancer
Interventions
RADIATION

Radiation therapy - 1 week

2600 cGy whole breast radiotherapy in five fractions (Arm 1) over 1 week

RADIATION

Radiation therapy - 2 weeks

3200 cGy whole breast radiotherapy with a concomitant tumor bed boost to 3600 cGy in 10 fractions (Arm 2) over 2 weeks. In Arm 2, if no cavity is visible due to oncoplastic surgery, we will deliver 32 Gy to the whole breast only, without a boost.

Trial Locations (3)

11215

RECRUITING

Brooklyn Methodist Hospital, New York

11355

RECRUITING

New York Presbyterian Hospital, New York

RECRUITING

New York-Presbyterian Weill Cornell Medical College, New York

All Listed Sponsors
lead

Weill Medical College of Cornell University

OTHER