ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG

NARecruitingINTERVENTIONAL
Enrollment

41

Participants

Timeline

Start Date

April 14, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

October 30, 2026

Conditions
Non-expandable LungTrapped LungPleural EffusionMalignant Pleural Effusions (Mpe)
Interventions
PROCEDURE

Air Entrainment - intentional introduction of the atmospheric air into the pleural space.

This intervention is distinct in that it uses a standard 3-way tap, already present in routine pleural drainage procedures, to intentionally introduce atmospheric air into the pleural space in a controlled and repeatable manner. Unlike other studies where air entrainment may occur incidentally or as part of more invasive procedures, this method specifically utilises precise manipulation of the tap handle to allow intermittent air entry, aiming to reduce negative intrapleural pressure and associated pain during fluid drainage. Air entry is carefully controlled, can be repeated up to five times per procedure, and does not interfere with fluid drainage or introduce additional equipment or complexity.

Trial Locations (1)

CB2 0BB

RECRUITING

Addenbrooke's Hospital, Cambridge

All Listed Sponsors
lead

Cambridge University Hospitals NHS Foundation Trust

OTHER