Effect of Dexmedetomidine on Hemodynamics in Cardiac Surgery

NACompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

May 5, 2022

Primary Completion Date

November 5, 2022

Study Completion Date

November 5, 2022

Conditions
Use of Dexmedetomidine in Cardiac Surgery (CABG, Valve Replacement or Total Aortic Arch Replacement)
Interventions
DRUG

Propofol group

In group P, 0.125 cc/kg saline infusion was administered in 10 minutes. Fentanyl was administered at a dose of 3 mcg/kg at 5 minutes of this application. Then propofol was administered until the eyelash reflex disappeared and the BIS value was 40. 0.6 mg/kg rocuronium was administered to facilitate intubation. All patients received 8 mg dexamethasone and lidocaine at a dose of 1 mg/kg.

DRUG

Dexmedetomidine

In group DP, dexmedetomidine at a dose of 0.5 mck/kg was administered over 10 minutes. At the 5th minute of this infusion, fentanyl was administered at a dose of 3 mcg/kg. Propofol was added until the BIS value was 40. The patients received 0.6 mg/kg rocuronium, 8 mg dexamethasone, and 1 mg/kg lidocaine.

Trial Locations (1)

20100

Pamukkale University, Denizli

All Listed Sponsors
lead

Pamukkale University

OTHER