Ultrasound vs. Surgical ESP Block With Bupivacaine-Dexmedetomidine in Lumbar Fusion Surgery

PHASE4RecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

May 6, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Post Operative Pain
Interventions
PROCEDURE

Ultrasound Guided erector spinae plane block (UB)

Ultrasound Guided erector spinae plane block (UB) with 40 ml Bupivacaine HCL mixed with 0.5 μg/kg dexmedetomidine .. After the surgical incision is closed and before extubation, while the patient remains in the prone position. A linear high-frequency transducer (L6-12 linear array transducer (6-12 MHz) on GE Healthcare logiq p7, made in Korea) will be positioned in a sagittal orientation, 4 cm lateral to the L3 transverse process. A 22 G × 88 mm block needle will be inserted in the craniocaudal direction, with the needle tip placed beneath the erector spinae muscle and above the hyperechoic transverse process. The needle tip position will be confirmed via saline injection. Once correct needle placement is verified, 40 mL of 0.25% bupivacaine, combined with 0.5 μg/kg dexmedetomidine 15 will be administered divided on both sides.

PROCEDURE

Surgical erector spinae plane block (SB)

Surgical erector spinae plane block (SB) with 40 ml Bupivacaine HCL mixed with 0.5 μg/kg dexmedetomidine ..This volume will be divided into 8 injections, four 5 ml injections on each side. The surgeons will perform the block just before starting the wound closure stage. The surgical ESP block technique consists of injections at four bilateral levels, starting from one level above the operated vertebra and covering all surgical segments using a 22G × 88 mm needle. The needle will be inserted to contact the transverse process, and the injectate will be delivered between the erector spinae muscle and the transverse process at each level.

DRUG

Dexmedetomidine

0.5 μg/kg dexmedetomidine added to block solution

DRUG

Bupivacaine Hcl 0.5% Inj

40 ml Bupivacaine HCL

Trial Locations (1)

63514

RECRUITING

Fayoum University hospital, Al Fayyum

All Listed Sponsors
lead

Fayoum University Hospital

OTHER