Intrathecal Fentanyl and Dexmedetomidine Added to Bupivacaine for Subarachnoid Anaesthesia for Percutaneous Nephrolithotomy

NAActive, not recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 10, 2025

Primary Completion Date

May 31, 2025

Study Completion Date

December 31, 2025

Conditions
Percutaneous Nephrolithotomy (PCNL)
Interventions
PROCEDURE

Intrathecal Fentanyl Group (F)

Group fentanyl (F), an injection of bupivacaine 0.5% (3.5 ml) + fentanyl 0.5 ml (25 μg) will be administered intrathecally.

PROCEDURE

intrathecal dexmedetomidine group(D)

Group dexmedetomidine( D), dexmedetomidine will be first diluted in normal saline to obtain a dose of 5 μg in 0.5 ml. Then, an injection of bupivacaine 0.5% (3.5 ml) + dexmedetomidine 0.5 ml (5 μg) will be administered intrathecally. Drug will be administered over 10 seconds (s) using 5 cc syringes with cephalad orientation of the spinal needle bevel.

Trial Locations (1)

21521

Faculty of medicine ,Alexandria university, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER

NCT06957301 - Intrathecal Fentanyl and Dexmedetomidine Added to Bupivacaine for Subarachnoid Anaesthesia for Percutaneous Nephrolithotomy | Biotech Hunter | Biotech Hunter