Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)

NANot yet recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

August 31, 2028

Study Completion Date

August 31, 2028

Conditions
PTSDTraumaPediatric ALL
Interventions
BEHAVIORAL

Emotion Regulation

Participants learn to reduce acute subjective distress, stabilize negative mood, promote positive mood, and alter physiological responses to trauma

BEHAVIORAL

Exposure

Participants engage in written exercises to reduce avoidance of trauma reminders and reinforce approach behaviors consistent with personal goals

BEHAVIORAL

Cognitive Processing

Participants learn ways to identify, challenge, and overcome the influence of cognitive distortions resulting from trauma exposure

BEHAVIORAL

Bi-lateral Stimulation

Participants engage in horizontal eye movements while recalling a traumatic memory and describing their affective and physiological state

BEHAVIORAL

Psychological Placebo

Participants receive non-directive support therapy, where they will guide the treatment session but not be required to discuss prior trauma exposure

All Listed Sponsors
lead

University of Rochester

OTHER