Platelet Derived Growth Factor Receptor ß (PDGFRß) Imaging in Cardiac Fibrosis

RecruitingOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
ST-Elevation Myocardial Infarction (STEMI)Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions
RADIATION

PET/MRI or separate PET/CT and MRI

"PET/MRI or separate PET/CT and MRI using the following imaging protocol: 15O-H20 (myocardial perfusion, up to 10 min dynamic PET scan), \[68Ga\]Ga-DOTA-Cys-ATH001 (PDGFRß PET, up to 60 min dynamic + static full body PET scans), and Gd-MRI (extracellular volume in infarct, around 10 min MRI scan).~Cohort 1 and 2 are examined twice, first one week after PCI/stent and then a second examination 2 to 8 months after the first. Cohorts 3, and 4 are examined once."

Trial Locations (1)

Unknown

RECRUITING

Uppsala University Hospital, Uppsala

All Listed Sponsors
lead

Uppsala University

OTHER

NCT06956560 - Platelet Derived Growth Factor Receptor ß (PDGFRß) Imaging in Cardiac Fibrosis | Biotech Hunter | Biotech Hunter